Details
BENEFITS:
- Regu-Mate effectively suppresses estrus in 95 percent of mares after 3 days of treatment.
- When treatment is discontinued, mares exhibiting regular estrous cycles return to estrus within 4 to 5 days following treatment and continue to cycle normally.
- Regu-Mate can help alleviate moodiness and temperament changes associated with estrus.
- It's easy to administer &ndash orally or top-dressed on grain.
- Horses, Mares
ACTIONS:
Regu-Mate altrenogest Solution 0.22% produces a progestational effect in mares.
INDICATIONS:
Regu-Mate altrenogest Solution 0.22% is indicated to suppress estrus in mares. Suppression of estrus allows for a predictable occurrence of estrus following drug withdrawal. This facilitates the attainment of regular cyclicity during the transition from winter anestrus to the physiological breeding season. Suppression of estrus will also facilitate management of prolonged estrus conditions. Suppression of estrus may be used to facilitate scheduled breeding during the physiological breeding season.
CONTRAINDICATIONS:
Regu-Mate altrenogest Solution 0.22% is contraindicated for use in mares having a previous or current history of uterine inflammation i.e., acute, subacute, or chronic endometritis. Natural or synthetic gestagen therapy may exacerbate existing low-grade or smoldering uterine inflammation into a fulminating uterine infection in some instances.
PRECAUTIONS:
Various synthetic progestins, including altrenogest, when administered to rats during the embryogenic stage of pregnancy at doses manyfold greater than the recommended equine dose caused fetal anomalies, specifically masculinization of the female genitalia.
WARNING:
For oral use in horses only. Keep this and all other medications out of the reach of children. Do not use in horses intended for human consumption.
HUMAN WARNINGS:
Skin contact must be avoided as Regu-Mate® (altrenogest) Solution 0.22% is readily absorbed through unbroken skin. Protective gloves must be worn by all persons handling this product. Pregnant women or women who suspect they are pregnant should not handle Regu-Mate® (altrenogest) Solution 0.22%. Women of child bearing age should exercise extreme caution when handling this product. Accidental absorption could lead to a disruption of the menstrual cycle or prolongation of pregnancy. Direct contact with the skin should therefore be avoided. Accidental spillage on the skin should be washed off immediately with soap and water.
INFORMATION FOR HANDLERS:
WARNING: Regu-Mate® (altrenogest) Solution 0.22% is readily absorbed by the skin. Skin contact must be avoided; protective gloves must be worn when handling this product.
Instructions
DOSAGE AND ADMINISTRATION:
It is important to follow your Veterinarian's prescription instructions for your horse.
While wearing protective gloves, remove shipping cap and seal; replace with enclosed plastic dispensing cap. Remove cover from bottle dispensing tip and connect luer lock syringe (without needle). Draw out appropriate volume of Regu-Mate® solution. (Note: Do not remove syringe while bottle is inverted as spillage may result.) Detach syringe and administer solution orally at the rate of 1 mL per 110 pounds body weight (0.044 mg/kg) once daily for 15 consecutive days. Administer solution directly on the base of the mare’s tongue or on the mare’s usual grain ration. Replace cover on bottle dispensing tip to prevent leakage. Excessive use of a syringe may cause the syringe to stick; therefore, replace syringe as necessary.
DOSAGE CHART:
Approximate Weight In Pounds
|
Dose in mL
|
770
|
7
|
880
|
8
|
990
|
9
|
1100
|
10
|
1210
|
11
|
1320
|
12
|
It is important to follow your Veterinarian's prescription instructions and cautions while administering this medication to your pet.
Ingredients
Each mL of Regu-Mate® (altrenogest) Solution 0.22% contains 2.2 mg of altrenogest in an oil solution.