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What You Need To Know

What You Need To Know

Cushings disease occurs when your pet’s body is producing excess cortisol, a hormone that helps their body respond to stress, control his weight, fight infections, and keep his blood sugar levels in check.  Since this stress hormone is key in controlling many important body functions you can expect symptoms in each of the areas that cortisol helps to control. I will discuss more of the symptoms in the sections called Tell Tail Signs.

AKA, Also Known As:

Cushing Disease is also known as hypercortisolism and hyperadrenocorticism

 

Did Stress cause Cushings Disease in my pet?:

No. The increased cortisol production can be related to the following disorders:

1.  excessive stimulation of the adrenal glands by the pituitary gland, usually as a consequence of a pituitary tumor (pituitary origin)
2.  the unregulated production of cortisol by the adrenal glands (adrenal origin)
3.  occasionally, administration of steroid-containing medications may result in the development of Cushing's disease (iatrogenic origin) such as corticosteroids like prednisone

Types of Cushings Disease

Cushings disease can involve two glands in the body, the adrenal gland and the pituitary gland. Therefore the types of Cushings involve both those glands

*  Pituitary dependent. I would say that this type of Cushings is the one I diagnose more often than Adrenal Dependent. It happens        when there’s a tumor in a pea-sized gland at the base of the brain, called the pituitary.
*  Adrenal dependent: This type comes from a tumor in one of the glands that sit on top of the kidneys, called adrenal glands. About      15% to 20% of diagnosed dogs will have this type.
*  There is a third kind of Cushings, called Iatrogenic. This is what our dog Lola had. She suffered from allergies for years and after       prolonged corticosteroid treatment she developed Cushings. Any long term steroid therapy,like Prednisone, Depomedrol or    allergy shots, can cause cushings due excess exogenous steroids (steroids that are not produced by the body but comes from an    external source). 
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