- A non-hormonal anti-inflammatory agent
- Relieves pain and inflammation
- Reduces fever
- for Horses
Possible Side Effects:
The most-common side-effects include ulceration of the mouth and GI tract. Less-common side-effects include renal damage, bleeding disorders and protein loss.
Use caution with patients who have a history of drug allergy.
Discuss your horses current medication, medical history or anything you feel is abnormal before your horses is given this medication.
NSAIDs should be avoided or very carefully monitored in animals with liver disease, kidney disease or GI problems. Therapy should be stopped at the first sign of any adverse reaction anorexiaoral ulcers, depression, decreased plasma protein, increased creatinine, anemia, leukopenia.
Work in rodents indicates that phenylbutazone may be harmful to the embryo. It can cross the placenta and is found in milk. Phenylbutazone should be avoided or used with caution in pregnant or nursing animals.
Pony breeds may be more susceptible to side effects from NSAIDs than horses. Older horses especially those with decreased kidney or liver function also may be more at risk for side effects. When NSAIDs are used in these populations, they should be used with caution and at the lowest effective dose.
Phenylbutazone may be used in foals, but it should be used with particular caution. Premature foals, septicemic foals, foals with questionable kidney or liver function, and foals with diarrhea require careful
monitoring. Drugs to protect the GI tract such as omeprazole, cimetidine and sucralfate are used frequently with phenylbutazone
In the treatment of inflammatory conditions associated with infections, specific anti-infective therapy should be used concurrently.
Not for use in horses intended for food.
Phenylbutazone may affect blood levels and duration of action of phentoin, valproic acid, sulfonamides, sulfonylurea antidiabetic agents, barbiturates, promethazine, rifampin, chlorpheniramine, diphenhydramine, penicillin G.
Avoid combining with other anti-inflammatory drugs that tend to cause GI ulcers, such as corticosteroids and other NSAIDs. Avoid combining with anticoagulant drugs particularly coumarin derivatives. Avoid combining with other hepatotoxic drugs
Dosage and Administration:
For horses only.
Follow your Veterinarians prescription instructions.
HORSES: Orally - The oral dose for horses is two 2 to four 4 grams 2 to 4 tablets per 1,000 lbs. of body weight every 24 hours
DO NOT EXCEED 4 GRAMS DAILY.
Reduce dosage as symptoms regress.
Intermittent treatment given only when symptoms appear