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  • Staphage Lysate Vaccine 10 ml Staphage Lysate Vaccine 10 ml

Staphage Lysate Vaccine 10 ml

by Delmont

$129.99 Suggested Retail Price: $155.99 You Save: $26.00

Please note: Express shipping required for this temperature sensitive product.



  • recommended for dogs suffering from recurrent pyderma.
  • It is the only staphylococcal product of its kind approved for canine use.


There are no known contraindications to the use of SPL except that in highly allergic patients reduced desensitizing doses may be indicated.


SPL does not contain a preservative; therefore, it must be handled aseptically. Do not use if it becomes cloudy. (This would indicate contamination.) Use entire contents when first opened.


The combination of initial and maintenance regimens requires an average of 3 vials or 3 packages of ampules per year per dog.

sterile technique must be used. 

Please read entire package insert before administering this product to your pet. Staphage Lysate injections are administered subcutaneously. 

SPL is administered by subcutaneous injection. The severity of the infection and the response of the patient should be the guiding factors in adjusting the dosage regimen.

All highly allergic patients (or those predisposed to allergy) should first be skin-tested to assess their relative sensitivity to SPL.

Although the chance of allergic reactions is very small, the patient should be observed for 45 minutes to 1 hour for immediate and for 48 hours for delayed reactions. Allergic reactions you might observe include weakness, vomiting, diarrhea, severe itching, and fast breathing.

For chronic, recurrent, refractory, or deep-seated infections, it may be necessary to increase cautiously the frequency and/or the dose to achieve the desired therapeutic response.

Following the initial injection, subsequent injections should avoid previous injection sites.

If an undue amount of local redness, itching, and/or swelling ensues, await a partial subsidence of the reactions, proceed with 1/2 the previous dose, and make incremental increases at longer intervals.

Staphylococcal Infections or Staphylococcal Hypersensitivity-Allergic Patients

Skin Test-0.05-0.1 mL intradermally.

Therapy-Initially 0.2 mL subcutaneously, then incremental increases of 0.2 mL once a week to 1.0 mL (a total of 5 injections). When you reach 1.0 mL, continue weekly injections of 1.0 mL for approximately 10-12 weeks.

Nonallergic Patients2

Skin Test-Not required for nonallergic patients.

Therapy-0.5 mL subcutaneously 2 times a week for 10 to 12 weeks, then 0.5 to 1.0 mL every 1 or 2 weeks.

Concomitant antibiotic therapy is recommended for an initial 4- to 6-week period.

The maximum dose should be decreased in small dogs and can be increased cautiously, if necessary, in large dogs to 1.5 mL. This dose is continued until improvement is demonstrated, then the interval may be lengthened gradually to the longest interval that maintains adequate clinical control.



Staphylococcus Aureus Phage Lysate - Staphage Lysate (SPL)® - is a bacteriologically sterile staphylococcal vaccine containing the components ofS. aureus, a bacteriophage, and some culture medium ingredients (sodium chloride and ultrafiltered beef heart infusion broth) in solution.

No chemical preservatives or inactivants are used in its preparation.

SPL is standardized on the basis of bacterial cell count before phage lysis. Each milliliter contains: 120-180 million colony-forming unit equivalents ofS. aureus and at least 100 million staphylococcus bacteriophage plaque-forming units.

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