Vetoryl Capsules

Benefits:

•  Promising treatment for Cushing's Disease in dogs 
•  Treats both pituitary-dependent and adrenal-dependent cases
•  Fewer & less severe side-effects reported than Mitotane
•  Controls excess production of cortisol

How does it work:

VETORYL Capsules are available in 3 sizes 10, 30 and 60 mg for oral administration based on body weight. Trilostane 4a, 5a-epoxy-17ß-hydroxy-3-oxoandrostane-2a-carbonitrile is an orally active synthetic steroid analogue that selectively inhibits 3 ß-hydroxysteroid dehydrogenase in the adrenal cortex, thereby inhibiting the conversion of pregnenolone to progesterone. This inhibition blocks production of glucocorticoids and to a lesser extent, mineralocorticoids and sex hormones while steroid precursor levels increase. 

Do not give this medication to dogs with kidney or liver disease. Vetoryl capsules should not be given to dogs taking certain medications or dogs that are pregnant. Speak with your veterinarian about all medications your dog is taking, including over-the-counter medicines.

Possible Side Effects:

Before giving Vetoryl tell your veterinarian if your pet is also taking ACE inhibitors such as enalapril, potassium sparing diuretics such as spironolactone, ketoconazole, or potassium supplements. Talk to your veterinarian or pharmacist before giving any prescription or over the counter medicines or nutritional supplements.

Vetoryl capsules should be given with food.

Trilostane