Details
Benefits:
- The only marketed FDA-approved* systemic treatment for dermatophytosis (ringworm) caused by Microsporum canis in cats.
- Itrafungol is a cost-effective
- Cherry caramel-flavored liquid that is easy to dose and easy to administer
- It requires a short course of pulse therapy oral dosing on alternate weeks for three treatment cycles.
Precautions:
Do not administer to cats with hypersensitivity to itraconazole. ITRAFUNGOL has not been shown to be safe in pregnant cats and should only be used in pregnant or lactating cats when the benefits outweigh the potential risks. Not for use in humans. Keep this and all medications out of reach of children. Wash hands and exposed skin after use. Use with caution in cats with renal dysfunction or impaired liver function. If clinical signs suggestive of liver dysfunction develop, treatment should be discontinued. ITRAFUNGOL is a cytochrome p-450 inhibitor and may increase or prolong plasma concentrations of other drugs metabolized by this pathway. Cats suffering from heart disease should be carefully monitored during treatment.
Possible Side Effects:
The most common adverse reactions reported in clinical trials include vomiting, diarrhea, decreased appetite and elevated hepatic enzymes.
Storage
Store at 68-77°F (20-25°C). Excursions permitted between 59-86°F (15-30°C).:
Instructions
It is important to follow your Veterinarian's prescription instructions for your pet.
Dosage and Administration:
The solution should be administered orally using the enclosed graduated dosing syringe.
The daily dosage is 5 mg/kg (0.5 mL/kg) body weight administered once daily on alternating weeks for 3 treatment cycles. Cats are treated during weeks 1, 3, and 5, and left untreated during weeks 2 and 4.
7 days
|
7 days
|
7 days
|
7 days
|
7 days
|
Daily treatment
|
No Treatment
|
Daily treatment
|
No Treatment
|
Daily treatment
|
Each line on the dosing syringe represents 0.05 mL of oral solution.
Table 1: Dose Table for ITRAFUNGOL
Weight of Cat
|
Volume of ITRAFUNGOL
|
0.5 lb
|
0.1 mL
|
1.0 lb
|
0.2 mL
|
1.5 lb
|
0.35 mL
|
2.0 lb
|
0.45 mL
|
2.5 lb
|
0.55 mL
|
3.0 lb
|
0.7 mL
|
3.5 lb
|
0.8 mL
|
4.0 lb
|
0.9 mL
|
4.5 lb
|
1.0 mL
|
5.0 lb
|
1.15 mL
|
6.0 lb
|
1.35 mL
|
7.0 lb
|
1.6 mL
|
8.0 lb
|
1.8 mL
|
9.0 lb
|
2.0 mL
|
10.0 lb
|
2.25 mL
|
11.0 lb
|
2.5 mL
|
12.0 lb
|
2.7 mL
|
13.0 lb
|
3.0 mL
|
The solution should be administered orally using the enclosed graduated dosing syringe. Keep the bottle upright and insert the dosing syringe through the opening of the top of the bottle (Figure 1). Do not invert the bottle (Figure 2). Fill the syringe by pulling the plunger until it reaches the graduation corresponding to the correct mL dose as indicated at the top of the syringe ring (Figure 3). Treat the cat by slowly and gently administering the liquid into the mouth, allowing the cat to swallow the product (Figure 4). For cats weighing more than 13.0 lbs, the total dose will need to be calculated and given over two doses as the dosing syringe only holds 3.0 mL of solution.
After dosing, the syringe should be removed from the bottle, rinsed and dried and the bottle cap should be screwed back on tightly.
Ingredients
itraconazole oral solution
10 mg/ml