How Adequan Canine Works
Adequan Canine polysulfated glycosaminoglycan is administered two times a week for four weeks. The drug is injected intramuscularly to ensure it reaches the critical parts of the joint. It goes to work in the joint in about two hours and stays in the joint for about three days.With Adequan Canine you should see signs of improvement within four weeks. Your dog may begin to act like the playful, active dog you remember.
Adequan Canine polysulfated glycosaminoglycan or PSGAG should not be used in dogs who are hypersensitive to PSGAG or who have a known or suspected bleeding disorder. It should be used with caution in dogs with renal or hepatic impairment. Possible side effects pain at injection site, diarrhea and abnormal bleeding were mild, transient and self-limiting. Safety studies of PSGAG in breeding, pregnant or lactating dogs have not been conducted.
Store at controlled room temperature up to 25°C (77°F) (See USP).
Frequently Asked Questions:
Q: What are the signs of canine arthritis?
It is important to note that arthritis occurs before clinical signs are shown. The beginning stages of this disease are not easily recognized. If your dog is suffering from arthritis, you will most likely see one or more of the following signs: lagging behind on walks, reluctance to walking, running, climbing stairs, jumping or playing. Additional signs may include: sluggishness, tiredness, low activity, reluctance to extend rear legs, aggressive or withdrawn behavior or other personality/behavioral changes.
Q: How do I know if my dog is at risk for this disease?
Canine arthritis does not discriminate. This disease can affect all breeds of dogs, but there are certain risk factors that you should be aware of, including: overweight, high activity levels for long periods of time, breed inherited traits, such as hip dysplasia, joint trauma, large breed and over the age of five.
Q: How does Adequan Canine polysulfated glycosaminoglycan or PSGAG work?
Adequan Canine is a prescription, water-based, intramuscular injection administered by your veterinarian. It helps keep the cartilage healthy and intact, so the bone in the joint cannot touch other bones. No other product for canine arthritis can do that.
Q: When should my dog be put on Adequan Canine?
To truly control canine arthritis, it is important to look at the big picture. If your dog is overweight, the veterinarian will likely prescribe a weight control diet. Exercise is also essential to facilitate an adequate supply of nutrition to the joint tissues. In addition, as soon as arthritis is diagnosed, you should ask your vet if Adequan Canine is right for your dog. As with any degenerative disease, treating it early is always best medicine.
Q: When will I see results with Adequan Canine?
With Adequan Canine you should see signs of improvement within four weeks. Your dog may begin to act like the playful and active dog you remember. To achieve the maximum benefits, it is important that your dog receives the entire four week eight-injection series.
Q: Are there any medical problems that my dog may have that would prohibit him from using Adequan Canine?
Adequan Canine should not be used in dogs showing hypersensitivity to PSGAG or in dogs with known or suspected bleeding disorders. It should be used with caution in dogs with renal or hepatic impairment. Safety studies in breeding, lactating, or pregnant dogs have not been conducted.
Q: Is Adequan Canine compatible with other medications that my dog may be taking?
You should always consult your veterinarian before combining Adequan Canine with other prescriptions or over the counter medications/supplements.
Q: How can I obtain Adequan Canine?
Adequan® Canine is a prescription product that can be dispensed and administered only by licensed veterinarians.
Adequan is manufactured by and is a registered trademark of Novartis. The information provided on this website is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. We reference Norvartis as the source for our information
Dosage and Administration:
The recommended dose of Adequan® Canine is 2 mg/lb body weight (.02 mL/lb, or 1 mL per 50 lb), by intramuscular injection only, twice weekly for up to 4 weeks (maximum of 8 injections). Do not exceed the recommended dose or therapeutic regimen. Do not mix Adequan® Canine with other drugs or solvents.
Each mL of Adequan® Canine contains 100 mg of PSGAG, 0.9% v/v benzyl alcohol as a preservative, and water for injection q.s. to 1 mL. Sodium hydroxide and/or hydrochloric acid added when necessary to adjust pH.