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Diphenhydramine is an antihistamine used to relieve allergy symptoms, insect stings, motion sickness, travel anxiety, and other conditions in both dogs and cats.

Allopurinol is a fast-acting prescription oral tablet, intended to prevent and dissolve urate bladder stones. Allopurinol is a xanthine oxidase inhibitor, which means it inhibits the production of uric acid, preventing the build up of the crystals in the urine that cause bladder and kidney stones. Allopurinol works by preventing the conversion of protein purines to uric acid. While Allopurinol prevents bladder and kidney stones, it can also dissolve stones that have already formed.