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  • Tri Heart Plus Chew Tabs for Dogs Tri Heart Plus Chew Tabs for Dogs
  • Tri Heart Plus Chew Tabs for Dogs Tri Heart Plus Chew Tabs for Dogs
  • Tri Heart Plus Chew Tabs for Dogs Tri Heart Plus Chew Tabs for Dogs
  • Tri Heart Plus Chew Tabs for Dogs Tri Heart Plus Chew Tabs for Dogs
  • Tri Heart Plus Chew Tabs for Dogs Tri Heart Plus Chew Tabs for Dogs

Interceptor Plus Chewable for Dogs


Sentinel Spectrum

Tri Heart Plus Chew Tabs for Dogs

by Merck

5 7

* Required Fields


This product requires a veterinarian's prescription.

This Rx product can not be shipped to some states.



  • Tri-Heart Plus protects your dog from heartworms, roundworms, and hookworms
  • Taken once a month
  • Safe to take all year round

Possible Side Effects:

Tri-Heart Plus is intended to prevent heartworm, hookworm and roundworm. Already infected dogs need to be de-wormed prior to administering Tri-Heart Plus. Additional side effects include anorexia, ataxia, convulsions, depression, diarrhea, hypersalivation mydriasis, staggering, and vomiting.


Blue - 25 lbs. and under, 6 pack  
Green - 26-50 lbs., 6 pack  
Brown - 51-100 lbs., 6 pack


Store Tri-Heart Plus in a cool, dry place. Keep Tri-Heart Plus away from light.


Keep Tri-Heart Plus in a secure area away from children or pets.



It is important to follow your Veterinarian's prescription instructions for your pet

Tri-Heart® Plus ivermectin/pyrantel chewable tablets should be administered orally at monthly intervals at the recommended minimum dose level of 6 mcg of ivermectin per kilogram (2.72 mcg/lb) and 5 mg of pyrantel (as pamoate salt) per kg (2.27 mg/lb) of body weight. The recommended dosing schedule for prevention of canine heartworm disease and for the treatment and control of ascarids and hookworms is as follows:

Dog Weight

Chewable Tablets per Month

Ivermectin Content

Pyrantel Content

Color Coding on Blister Card and Carton

Up to 25 lbs


68 mcg

57 mg


26 to 50 lbs


136 mcg

114 mg


51 to 100 lbs


272 mcg

227 mg


Tri-Heart® Plus ivermectin/pyrantel chewable tablets are recommended for dogs 6 weeks of age and older. For dogs over 100 lbs, use the appropriate combination of these tablets.

ADMINISTRATION: Remove only one chewable tablet at a time from the blister card. Because most dogs find Tri-Heart® Plus chewable tablets palatable, the product can be offered to the dog by hand. Alternatively, it may be added intact to a small amount of dry food or placed in the back of the dog’s mouth for forced swallowing.

Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes after administration to ensure that part of the dose is not lost or rejected. If it is suspected that any of the dose has been lost, redosing is recommended.

Tri-Heart® Plus chewable tablets should be given at monthly intervals during the period of the year when mosquitoes (vectors), potentially carrying infective heartworm larvae, are active. The initial dose must be given within a month (30 days) after the dog’s first exposure to mosquitoes. The final dose must be given within a month (30 days) after the dog’s last exposure to mosquitoes.

When replacing another heartworm preventive product in a heartworm disease preventive program, the first dose of Tri-Heart® Plus chewable tablets must be given within a month (30 days) of the last dose of the former medication.

If the interval between doses exceeds a month (30 days), the efficacy of ivermectin can be reduced. Therefore, for optimal performance, the chewable tablet must be given once a month on or about the same day of the month. If treatment is delayed, whether by a few days or many, immediate treatment with Tri-Heart® Plus chewable tablets and resumption of the recommended dosing regimen minimizes the opportunity for the development of adult heartworms.

Monthly treatment with Tri-Heart® Plus chewable tablets also provides effective treatment and control of ascarids (T. canis, T. leonina) and hookworms (A. caninum, U. stenocephala, A. braziliense). Clients should be advised of measures to be taken to prevent reinfection with intestinal parasites.


Tri-Heart Plus contains Ivermectin and Pyrantel pamoate

Additional Information

Is Rx Product Yes

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