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  • Synotic Otic Solution Synotic Otic Solution

Synotic Otic Solution

by Zoetis

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This product requires a veterinarian's prescription.

This Rx product can not be shipped to some states.



* Corticosteroid relieves inflammation and itching of the ears
* The DMSO improves the absorption of the corticosteroids and has anti-inflammatory properties
* Topical medication is easily absorbed through the skin


SYNOTIC Otic Solution Veterinary is indicated for the relief of pruritus and inflammation associated with acute and chronic otitis in the dog.


DMSO may cause a garlic or oyster-like breath and taste in the mouth. Corticosteroids with DMSO may cause a short, stinging sensation, especially on open skin, and a temporary increase in temperature of the treated area may be noticed.

If ingested or given at high doses for an extended period of time, the most common side effect of corticosteroids with DMSO is an increase in the amount of drinking and urinating. Less commonly, you may see an increased appetite, a change in weight, panting, diarrhea, vomiting, and behavior changes. Consult your veterinarian if you notice any of the above side effects.

If your pet experiences an allergic reaction to the medication, signs may include facial swelling, hives, scratching, sudden onset of diarrhea, vomiting, shock, seizures, pale gums, cold limbs, or coma. If you observe any of these signs, contact your veterinarian immediately.


Store Synotic at room temperature in a tight, light-resistant, childproof container. Keep out of the reach of children and pets.


There should be careful initial evaluation and follow-up of infected ears. Incomplete response or exacerbation of corticosteroid responsive lesions may be due to the presence of an infection which requires identification or antibiotic sensitivity testing, and the use of the appropriate antimicrobial agent. As with any corticosteroid, animals with a generalized infection should not be treated with this product without proper supportive antimicrobial therapy. Preparations with DMSO should not be used in pregnant animals since studies in chick embryos and guinea pigs have indicated it is teratogenic and embryotoxic.



Follow your Veterinarian's prescription instructions for your pet.

The recommended dose of SYNOTIC Otic Solution Veterinary is 4 to 6 drops 0.2 mL per ear administered twice daily into the ear canal for a maximum period of 14 days. The total dosage used should not exceed 17 mL. It is recommended that the affected ear canal be cleansed by some appropriate method prior to the instillation of the solution. 

Following instillation, gentle external massage of the ear canal may aid in promoting an even distribution of the medication. 
Care should be taken to avoid contact of the medication with the dog'S eyes. 
Contact of the bare hand with the medication should also be avoided. 



Additional Information

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