- Lysodren (mitotane) is used in veterinary medicine to treat dogs with Cushing's disease.
Possible Side Effects:
You may see lethargy, weakness, lack of appetite, vomiting, diarrhea, incoordination, or depression.
May cause liver damage, which could result in loss of appetite and jaundice yellowing of the gums, skin, or eyes.
Consult your veterinarian if you notice any of the above side effects.
As the drug becomes effective, you will notice a decrease in your pet's food and water intake, and urination.
If your pet experiences an allergic reaction to the medication, signs may include facial swelling, hives, scratching, sudden onset of diarrhea, vomiting, shock, seizures, pale gums, cold limbs, or coma.
If you observe any of these signs, contact your veterinarian immediately.
Tell your veterinarian if your dog has liver or kidney disease, diabetes, or could be pregnant. Notify your veterinarian of any other medications or supplements your pet is taking, and also if your pet has had any reactions to previous medications.
Fully understand your veterinarian's instructions and what side effects of the drug to watch for.
Wear gloves and wash your hands after giving Lysodren to your dog.
Not for use in animals hypersensitive allergic to it or drugs similar to it.
Do not use in pregnant or lactating animals female animals nursing their young.
Use with caution in animals with liver or kidney disease.
Pregnant women or women trying to get pregnant should not handle this medication.
Wear gloves when handling this medication.
Wash hands after handling the medication.
It can be very toxic.
Do not allow Lysodren to enter the environment through the soil or water.
Any leftover drug should be returned to your veterinarian for disposal.
Consult your veterinarian before using with any other medications, including vitamins and supplements, prednisone, prednisolone, barbiturates, warfarin, phenobarbital, or spironolactone, since interactions may occur.
May see an increase in depressant effects if given with other central nervous system CNS depressants.
Starting therapy with this drug may cause a rapid change in the insulin requirement of diabetic animals.
Dosage and Administration:
Follow your Veterinarian's prescription instructions.
Lysodren is given orally, with food, preferably a food high in fat content to increase absorption.
Lysodren is usually given at high doses for the first 1-10 days, and then the dose is lowered under the direction of the veterinarian.
Your veterinarian will work with you closely to determine when the dose is changed and by how much.
This medication should only be given to the pet for whom it was prescribed.